Intra-articular Injection for the Management of Rheumatoid Arthritis Patients with Knee Osteoarthritis-Current Evidence and Future Prospects
نویسنده
چکیده
Intra-articular injection of hyaluronic acid (HA) is well known to improved pain and function in patients with osteoarthritis (OA) [1,2]. As for rheumatoid arthritis (RA) patients with knee osteoarthritis, current medication for injection therapy includes steroid, hyaluronic acid, and platelet-rich plasma (PRP). In this article, we collected current studies regarding to this issue and suggest future possible research direction.
منابع مشابه
Histological assessment of intera articular injection of 90Y- hydroxyapatite radiocolloid in enrofloxacin induced rheumatoid arthritis in rat models
Histological assessment of intera articular injection of 90Y- hydroxyapatite radiocolloid in enrofloxacin induced rheumatoid arthritis in rat models Introduction: Rheumatoid arthritis (RA) is one of the most common and disabling diseases in societies that causes chronic synovial inflammation and joint damages. Several pharmaceutical and non-pharmaceutical treatments of RA have been developed...
متن کاملThe Role of Gene Therapy in Cartilage Repair
The key principle of gene delivery to articulations by direct intra-articular injection is to release complementary DNA(cDNA)-encoding medical products that will lead to maintained, endogenous production of the gene products withinthe articulation. In fact, this has been accomplished for both in vivo and ex vivo gene delivery, using several vectors,genes, and cells in some animal models. Some c...
متن کاملHistopathological changes of the antigen-induced chronic arthritis in the knee joint of the rabbit
Background and Objectives: The cause and pathophysiology of rheumatoid arthritis has not been fully understood and an experimental model of this disease is essential for research on the problem. In this research study, establishment and histopathological changes of chronic arthritis due to intra-articula...
متن کاملEffect of intra-articular injection of hyaluronic acid in rheumatoid arthritis patients with knee osteoarthritis.
BACKGROUND Intra-articular injection of hyaluronic acid (HA) is a well-documented treatment for knee osteoarthritis (OA). One of the multifactorial mechanisms is that exogenous HA can stimulate endogenous HA production. HA can regulate the growth and function of chondrocytes by binding to CD44 receptors on the chondrocytes. Synovitis is often found in patients with rheumatoid arthritis (RA) and...
متن کاملPatient Satisfaction Following Total Knee Arthroplasty: Comparison of Short-Term Results in Rheumatoid Arthritis and Osteoarthritis
Background: Due to the obvious differences in the natural course of rheumatoid arthritis (RA) and osteoarthritis (OA),different functional outcomes might be expected after Total Knee Arthroplasty (TKA) in these distinct patients. Althoughseveral studies have reported the objective outcome of TKA in RA and OA patients, few studies have compared postoperativepatient-satisfaction levels.Methods: I...
متن کامل